Evidence of inbreeding depression – a prospective study in the population of the European Dobermann – by Professor Sonia Garzia (2011) Introduction: Modern purebred dogs are plagued by many kinds of heritable diseases. The high prevalence of diseases and defects in pure dog breeds are due to high selection intensities in genetically closed populations (Ubbink… Read More »
Single-Nucleotide-Polymorphism Based Association Mapping of Dog Stereotypes by Paul Jones – Kevin Chase – Alan Martin – Pluis Davern – Elaine A. Ostrander – Karl G. Lark ABSTRACT Phenotypic stereotypes are traits, often polygenic, that have been stringently selected to conform to specific criteria. In dogs, Canis familiaris, stereotypes result from breed standards set for… Read More »
Genetic regulation of canine skeletal traits – trade-offs between the hindlimbs and forelimbs in the fox and dog – by Anastasia V. Kharlamova – Lyudmila N. Trut – David R. Carrier – Kevin Chase – Karl G. Lark Synopsis Genetic variation in functionally integrated skeletal traits can be maintained over 10 million years despite bottlenecks… Read More »
Genetic diversity of dog breeds – between-breed diversity, breed assignation and conservation approaches – by G. Leroy – E. Verrier – J. C. Meriaux – X. Rognon Summary Genetic relationships between 61 dog breeds were investigated, using a sampling of 1514 animals and a panel of 21 microsatellite markers. Based on the results from distance-based… Read More »
Average onset of DCM by Bitten Jönsson (2013) In our breed females starts to develop DCM around the age of 8 years …. A quite interesting statement, especially when the average lifespan in females diagnosed with heart problem/DCM is approx. 7,14 years. In addition to this, from diagnose and with appropriate medication, the average lifespan… Read More »
Inbreeding IDC Show Winners from 1979 to 2010 by Bitten Jönsson Statistic for IDC Show Winners from 1979 to 2010 In the following diagram an overview of the COI in %, of the dogs which have won, at the IDC within the mentioned period of time. We here find evidence of, that the COI mean… Read More »
Inbreeding Leistungssiegers from 1950 to 2012 by Bitten Jönsson Statistic of COI within DV-Leistungssiegers 1950-2012 Note – the gabs in the diagram is due to, that no DV-Leistungssieger competition were held in1958 and 1969. Comparing the COI mean of 16,83% over 13 generations to the COI breed mean of approx. 21% – we find that… Read More »
Diagnostische Parameter für die dilatative Kardiomyopathie beim Dobermann von Judith Mäurer (2010) EINLEITUNG Die dilatative Kardiomyopathie ist mit Prävalenzen bis zu 62 % die häufigste Herzerkrankung beim Dobermann. Es handelt sich um eine Erkrankung mit einem autosomal dominanten Erbgang, von der hauptsächlich ältere Dobermänner betroffen sind. Der Verlauf der Krankheit, der durch eine okkulte Phase… Read More »
INVASIVE HEMODYNAMIC MONITORING: PHYSIOLOGICAL PRINCIPLES AND CLINICAL APPLICATIONS by Jan M. Headley, RN, BS, CCRN Irvine, California INTRODUCTION During the last 25 years, the art of critical care medicine has greatly changed. This process has been due in part to the formation of specialized units for patient care, advances in technology, and a better understanding… Read More »
A Prospective Genetic Evaluation of Familial Dilated Cardiomyopathy in the Doberman Pinscher by Kathryn M. Meurs, Philip R. Fox, Michelle Norgard, Alan W. Spier, Allison Lamb, Shianne L. Koplitz, and Ryan D. Baumwart Background: The Doberman Pinscher is one of the most common breeds of dogs to develop dilated cardiomyopathy (DCM), a primary heart muscle… Read More »